Re2O
Skin booster made from acellular human dermal matrixRe2O at a glance
- Price
- From ₩490,000 · 2 options See all prices
- Ingredient
- Polynucleotide (PN), purified DNA fragments
- Maker
- PharmaResearch, South Korea
- Amount
- 2 to 4 cc for the full face, 1 cc for a small area
- Course
- At least 3 sessions, 2 to 3 weeks apart
- Numbing
- Topical anesthetic cream before treatment
- Makeup
- From the next day
Visiting Seoul for a short stay
Plan at least 3 sessions 2 to 3 weeks apart. You can wash and wear makeup from the next day; for 3 to 7 days skip heavy drinking, smoking, saunas, hot baths and hard exercise.

Your visit at Beauty Z
- ConsultationA doctor assesses your skin and agrees the plan with you.
- CleansingYou wash off makeup and sunscreen at the clinic.
- Numbing creamNumbing cream is applied to the treatment area.
- TreatmentThe doctor injects small amounts of Rejuran Healer across the face. Small bumps usually settle within 2 to 3 hours.
- Aftercare adviceYou receive aftercare instructions before you leave.
Rejuran Healer and Rejuran HB
Rejuran HB combines the same polynucleotide with hyaluronic acid. Your doctor recommends one or the other, or a combination with other boosters, after checking your skin.

Common questions
- What is Rejuran Healer?
- Rejuran Healer is a skin booster injection made by PharmaResearch in South Korea. Its ingredient, polynucleotide (PN), is made of purified DNA fragments derived from salmon. Injected into the skin layers, PN promotes regeneration of the epidermis and dermis, softening fine lines, refining pores and improving elasticity. It also moisturizes dry skin and reduces sebum in oily skin.
- How many Rejuran sessions do I need?
- At Beauty Z Clinic Myeongdong, we recommend at least 3 sessions spaced 2 to 3 weeks apart. Effects and how long they last vary by person, and your doctor sets the plan with you at consultation.
- Will I see small bumps?
- Small raised bumps from the product usually settle within 2 to 3 hours but can last 1 to 2 days.
- When can I have a facial massage?
- Avoid rubbing the treated area, and skip intense or deep facial massage for one month.
Sources: Polynucleotides in aesthetic medicine (PMC review) · Beauty Z Clinic Myeongdong treatment notes and price list. Results differ from person to person; your doctor will advise at consultation.
Re2OTreatment overview
Re2O (Elravie Re2O, made by L&C Bio) is a skin booster made from donated human dermal tissue with the cells removed.
It supplies moisture and nutrients to the deep layers of the skin to improve skin texture, elasticity, radiance and vitality.
Its matrix is mostly collagen, with some elastin, and it is injected directly into the skin. It helps dry, dull skin look more hydrated and smooth.


Re2ORecommended for
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point 01.
Dry, dull-looking skin
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point 02.
Fine lines and reduced elasticity
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point 03.
Smoother, brighter skin texture
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point 01.
Re2OResults and frequency
-
01.
Results vary with skin condition. We recommend 3 or more treatments, spaced 2 to 4 weeks apart.
-
02.
You can feel better hydration and smoother skin texture right after treatment, and with repeated treatments, elasticity, radiance and fine lines gradually improve.
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01.
Re2OQ&A
- Q.How is Re2O different from other hydration injections?
- Re2O is a matrix of collagen, elastin and sGAGs from donated human dermal tissue, so it supports hydration, elasticity and skin texture together.
- Q.Can it be combined with Rejuran Healer?
- Yes. Rejuran Healer focuses on skin regeneration, while Re2O helps with hydration and maintaining elasticity, so you can expect a synergistic effect when the two are given together.

Re2OAftercare
- -You can cleanse and wear makeup starting the day after treatment.
- -Avoid rubbing or irritating the treated area, and wait 1 to 2 weeks before having any facial massage.
- -For 2 to 3 days after treatment, avoid alcohol, smoking, saunas, jjimjilbangs (Korean bathhouses) and strenuous exercise.
- -Swelling, redness and bruising may occur after treatment. Most of these resolve on their own within 2 to 3 days.
- -Right after treatment, focus on moisturizing and sun protection. A skin regeneration cream also helps with recovery.
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