Will I see small bumps after the injections?

Small raised bumps from the product usually flatten within 2 to 3 hours, but can last 1 to 2 days depending on skin condition.

When can I have a facial massage?

Avoid rubbing the treated area, and skip intense or deep facial massage for one month.

Will there be bruising?

Bruising and swelling can occur with injections depending on skin condition, but they are usually minimal and settle quickly.

How long does the treatment take, and what is the recovery time?

The treatment takes about 15 minutes, not including anesthesia time, and you can return to your daily routine right afterward.

How is it different from the original Rejuran Healer?

Rejuran HB contains PN, the original Rejuran ingredient, along with the moisturizing ingredient HA (hyaluronic acid) and the anesthetic lidocaine. You can expect the regeneration and elasticity benefits of PN plus hydration from HA. The local anesthetic makes the injections more comfortable.

Rejuran HB

Polynucleotide with hyaluronic acid for regeneration and hydration

Rejuran HB at a glance

Price: From ₩139,000 · 2 options See all prices
Maker: PharmaResearch, Korea
Ingredients: Salmon-derived PN and hyaluronic acid, 1:1
Numbing: Lidocaine 0.3% in the syringe, plus topical anesthesia
Treatment time: About 15 minutes, plus numbing time
Course: At least 3 sessions, 2 to 3 weeks apart
Makeup: Cleansing and makeup from the next day

Visiting Seoul for a short stay

The clinic recommends at least 3 sessions 2 to 3 weeks apart. You can wash and wear makeup from the next day; avoid alcohol, smoking, saunas, hot baths and hard exercise for 3 to 7 days, and skip intense massage for one month.

Beauty Z Skin Clinic Myeongdong, model visual

Your visit at Beauty Z

ConsultationA doctor assesses your skin and agrees the plan with you.
CleansingYou wash off makeup and sunscreen at the clinic.
Numbing creamNumbing cream is applied to the treatment area.
TreatmentAfter you cleanse your face and topical numbing takes effect, the doctor injects Rejuran HB into the skin of the treatment area.
Aftercare adviceYou receive aftercare instructions before you leave.

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Common questions

Will I see small bumps after the injections?: Small raised bumps from the product usually flatten within 2 to 3 hours, but can last 1 to 2 days depending on skin condition.
When can I have a facial massage?: Avoid rubbing the treated area, and skip intense or deep facial massage for one month.
Will there be bruising?: Bruising and swelling can occur with injections depending on skin condition, but they are usually minimal and settle quickly.

Corridor, Beauty Z Skin Clinic Myeongdong

Reception, Beauty Z Skin Clinic Myeongdong

Sources: Clinical, Cosmetic and Investigational Dermatology 2025: Rejuran HB plus, 1% PN, 1% HA, 0.3% lidocaine (PharmaResearch) · Journal of Cosmetic Dermatology 2025: REJURAN HB contains 0.3% lidocaine · Beauty Z Skin Clinic Myeongdong treatment notes and price list. Results differ from person to person; your doctor will advise at consultation.

Rejuran HBTreatment overview

Rejuran HB (Hydro Booster) combines PN, the salmon-derived ingredient in the original Rejuran, with hyaluronic acid (HA) in a 1:1 ratio. HA is a polysaccharide found naturally in the body. It is known for holding moisture well and is used in hydrating injections.
Rejuran HB adds hydration to the regenerating effect of Rejuran and contains lidocaine, a numbing agent. It can help improve skin tone and texture, pores and fine lines.
Rejuran HBRecommended for
- point 01.
  Anyone worried about pain from injection treatments
- point 02.
  Damaged skin that needs regeneration
- point 03.
  Better skin elasticity and hydration
Rejuran HBResults and frequency
- 01.
  Results and how long they last vary by person. We recommend at least 3 sessions, spaced 2 to 3 weeks apart.
Rejuran HBQ&A
- Q.
  How long does the treatment take, and what is the recovery time?
- The treatment takes about 15 minutes, not including anesthesia time, and you can return to your daily routine right afterward.
- Q.
  How is it different from the original Rejuran Healer?
- Rejuran HB contains PN, the original Rejuran ingredient, along with the moisturizing ingredient HA (hyaluronic acid) and the anesthetic lidocaine. You can expect the regeneration and elasticity benefits of PN plus hydration from HA. The local anesthetic makes the injections more comfortable.
Rejuran HBAftercare
- -You can cleanse and wear makeup starting the day after treatment.
- -To prevent inflammation, avoid heavy drinking, smoking, saunas or jjimjilbang (Korean bathhouses), hot baths, and vigorous exercise for 3 to 7 days after treatment.
- -Avoid rubbing or putting strong pressure on the treated area. Skip intense or deep facial massage for one month.
- -Small bumps from the product usually settle within 2 to 3 hours but may last 1 to 2 days depending on skin condition.
- -Injections may cause bruising and swelling depending on your skin condition. These are usually mild and subside quickly.